Articles Tagged With:
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Family Might Have Valid Reasons to Override Patient’s Advance Directive
Ethical conflicts often arise when families seek to override a patient’s advance directive. Ethicists guide clinicians through complex cases, weighing patient intent, medical changes, and best interests while addressing emotional and legal tensions around end-of-life care decisions.
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New Data Inform Decision-Making on Withdrawal of Life-Sustaining Therapy Timing
New research challenges assumptions about prognosis in severe traumatic brain injury cases, showing some patients recover well despite poor indicators. Ethicists emphasize caution and individualized decisions.
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Does an Elevated Troponin Level Post-Exercise Indicate Occult Coronary Atherosclerosis?
In middle-aged competitive recreational athletes, increases in cardiac troponin levels with exercise competitions were not infrequent. In a subgroup, coronary artery calcium by computed tomography was found in almost two-thirds, but the prevalence and magnitude of calcium was not associated with the exercise troponin response.
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Does Lipoprotein(a) Improve the Risk Calculation of the PREVENT Equation?
A pooled cohort from the Multi-Ethnic Study of Atherosclerosis and the United Kingdom Biobank study has shown that, overall, the American Heart Association PREVENT risk scores performed well at predicting atherosclerotic cardiovascular disease risk even in those with high lipoprotein(a) levels, but considering lipoprotein(a) in those with low PREVENT scores may help make therapeutic decisions in these individuals.
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Benefits of Nudging in Severe Aortic Stenosis
A single health system study of electronic provider notifications when severe aortic stenosis was discovered on echocardiography showed that referrals for aortic valve replacement significantly increased, especially in women and those > 80 years of age.
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Balloon Angioplasty for Chronic Thromboembolic Pulmonary Hypertension
A multinational, prospective registry of balloon pulmonary angioplasty has shown that significant improvement in patients with chronic thromboembolic pulmonary hypertension can be accomplished with few complications and no periprocedural mortality.
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Complications with the First Transcatheter Tricuspid Valve: Real-World Analysis
This review of complications seen in real-world practice with the Evoque transcatheter tricuspid valve highlights the need for careful patient selection and operator training with this technology.
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Gepotidacin Tablets (Blujepa)
The U.S. Food and Drug Administration has approved gepotidacin, a first-in-class antibacterial medication for the treatment of uncomplicated urinary tract infections. It is the first new class of oral antibiotics approved in nearly 30 years.
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Vasectomy Follow-Up Rates: How Good Are They?
In this retrospective cohort study of 2,567 patients at a single institution, 42.1% of men did not follow up at all after vasectomy for semen analysis. Of those with spermatozoa on the initial testing post-vasectomy, 43.3% of men failed to return for repeat testing.
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Can Hyperemesis Gravidarum Be Prevented with Metformin?
Although differences were not statistically significant, women with pre-conceptional metformin exposure appeared to have lower rates of hyperemesis gravidarum and comparable nausea and vomiting symptom severity, suggesting a potential protective effect that warrants further investigation in larger, adequately powered studies.